ملخص البحث :

The survey aimed to evaluate the situation of oxidative stress in sufferers with CRD via measuring some biochemical variables within the serum of 65 wholesome human beings as a control group among the a while of 38-60 years, and the sera of 60 sufferers with CKD, old between 65 and 40 years attended to (The artificial kidney unit) of Murjan scientific city whom are identified via specialist doctors.Results: Significant increase are observed in urea, creatinine and albumin, in addition to malondialdehyde degree for renal suffererscompared with the control cohort, at the same time as confirmed stages of glutathione peroxidase and catalase and glutathione a tremendous lower in patients with renal failure while as compared with the monitoring set. Additionally did score level ceruplasmin, and nitric oxide statistically big difference

ملخص البحث :

The aim of the study is to detect whether Bardoxolone is effective in treatment of colonic carcinoma by apoptosis and regression of tumor markers and activation of tumor suppressor genes as compared to other FDA approved anticancer agents as 5-FU. colonic cancer cell line (HCT 116). These cells are cultured in vitro according to routine cell culture protocols using specific media and reagents.