ملخص البحث :

The aim of the study is to valuation some biomarker biochemical parameters that play important role in evaluating functions renal for hypertensive. The study was obtained. Included ninety-one. 35(38.46 %) of the objects were males and 56 (61.54 %) were females. forty-two (42) subjects were selected as control and forty nine (49) suffered only from essential hypertension with high mean body mass index (Mean 35.70 3.38 S.E) (Kg/m²). The data of the study indicate a significant (p<0.05) raise in the rate of age (Mean49.89±10.36) (years), body mass index (Mean 35.70± 3.38 S.E) (Kg/m2), SBP(Mean14.77±0.75 S.E) (mmHg) and DBP(Mean 9.6910.72 S.E) (mmHg) for patients with hypertensive compared with healthy people. As for the biochemical parameters the results showed a significant (p-0.05) increase in concentration serum Cystatin C (Mean1.21 ± 0.44S.E) (mg/L), Creatinine(Mean 1.062+0.36 S.E) (mg/dl) .urea (Mean 7.76 0.55 S.E) (mmol/l)and uric acid(Mean 4.7740.82 S.E) (mg/dl). As for the Correlation coefficient of linear regression analysis of diastolic blood pressure with the biochemical parameters did not show any significant correlation, while the results linear regression analysis showed positive correlation between systolic blood pressure with cystatin C (y-0.38x-4.38 SBP), Creatinine( y=0.37x-4.37 SBP) and uric acid (y-0.1*x-10*SBP).

ملخص البحث :

Objective: This study aimed to evaluate the relationship between thalassemia disease and body mass index (BMI) and the correlation with blood group of thalassemia patients. Methods: The study includes 260 persons (male+female), 200 persons were thalassemia patient (120 male and 80 female), and 60 healthy persons (30 male and 30 female) as control group; furthermore, people were divided into three group according to age 1-9, 10-19, and >20 years, and BMI and blood group were measured for all patients and healthy people. Results: The results showed that the frequency of thalassemia in male (65%) is higher than in female (40%); as well as, the results showed that the age group (10-19) years is more frequent in male, while in female, the age group (1-9) years is more frequent. The results of BMI revealed a significant decrease (p<0.05) in all groups of thalassemia patients compared with healthy group; as well as, the results of blood group showed that the group (0+) is the more frequent 34% in comparison with the other blood groups. Conclusion: We conclude that there was a strong relationship among gender, blood group (the most common blood group observed is O +ve), and BMI with thalassemia.

ملخص البحث :

The present study was performed to estimate some physiological parameters in patients with asthma, as well as the correlation between this disease and sex in three age groups. This work was applied on 59 asthmatic patients (23 male and 36 female) and 30 apparently healthy subjects (14 male and 16 female) as control group. The study reveals that the level of estradiol was increased significantly ( P< 0.05 ) in females compared with males, while there has been a raise in the level of estradiol of patient in the age groups (1-10), (11-20), and (31- 40) years in comparison with the with the categories (21-30) and ( > 50 ), in addition, there was higher increase in its level through the duration of the most illness than ten years, while the results of the study presented a clear difference ( P< 0.05 ) in the RBCs count of males with asthmatic compared to females. The data also displayed an obvious difference ( P< 0.05 ) in the platelets of patient males compared with healthy males, there is an increase ( P< 0.05) in the means of PCV and Hb in the age group ( > 50 ) in contrast with (1-10), (11-20) (21-30) and (31-40) groups, the results showed a significant variance in the platelets count between patients and healthy in the age group (1-10) as well as, there was a significant variance in the mean of RBCs count, PCV and Hb in the duration of illness > 10 years compared with the duration of the illness (1-5) years and (6-10) years

ملخص البحث :

Background: The liver is the major organ in the body and it is considered as an important organ for protein manufacture and detoxification. Liver health is evaluated by study liver function (LFTs) which include TSB, AST, ALT and ALK. The current study is an attempt to understand the correlation between morbid obesity and liver function enzymes. Method: The research population consisted of 67 subjects that divided into two groups; morbidly obese group (41) and the control group (healthy appearance subjects) (26). The levels of serum liver enzymes activities (ALT, AST, ALK) and TSB were determined by suitable kits. Result: In current study no statistically significant differences were observed in AST, ALT and ALK levels between the two types of procedures. The highest differences were noted for TSB levels between obese and individual healthy. While there was an association between the BMI and both AST and ALT; there was no relationship between the body mass index BMI and TSB and ALK. Conclusion: This study showed a correlation between the BMI with AST and ALT of morbidly obese.

ملخص البحث :

Background: The eye is one of the important sensation members in our life. Health guidelines that are given to eye soundness and neatness are important because of many factors where dust, high temperature, microorganisms and other agents can cause many diseases of the eye which may lead to blindness. This study included the investigation of the bacterial species causing inflammation of the eye which include conjunctivitis, eye lid infection and cornea at different age groups. Method: One hundred and forty three swabs were collected from eyes of infected people in addition to 110 blood samples of people who visited Al-Hilla teaching hospital and Alnoor hospital for Children from December 2017 to Jun 2018. Culture investigations showed 137 positive bacterial growth and 6 without growth. Staphylococcus aureud was the most common isolate 48(35.0%) of the total samples followed by E.coli 20(14.59%) followed by S. pneumoniae 18(13.13%) followed by S. epidermis 17(12.4%) followed by Enterococcus 10(7.299%) followed by K. pneumoniae 8(5.8 3%) followed by H. influenzae 7(5.1%) followed by P. aeruginosae 6(4.37%) followed by N gonorrhoeae 2(1.45% ) . Also, the study transacted with determination of cytokines concentration. Results and Conclusion: IL-8 showed elevated concentrations particularly in age group (1- 10) year as it reached 282.67+20.53pg/ml compared to controls 134-97.51pg/ml. Also, IL-1 concentration was higher in patients than in controls particularly in age group (51-60) years as it reached 352.67-46.49pg/ ml compared to controls 27049.54.

ملخص البحث :

From a group of pre and post-menopausal women, respectively (34 and 46) were selected as test samples as well as 24 healthy women as control samples. All the test and control samples evaluated to measure the Total Vitamin level, Anti Mullerian hormone, and HMGB1 level. The study was planned to assess the relationship between Vit. D. level, AMH, and HMGB1 at the Babylon women at age < 45 years as (Pre – Menopausal) and > 45 years as Post-menopausal. The time between sample collection and measure of the studied parameters was in between (Jullay 2019 – Until January 2020) in Merjan medical city, GIT, and Live Center laboratory. Pre-menopausal women show a low level of AMH in comparison with postmenopausal and control samples. postmenopausal women show a low level of HMGB1 in comparison with the premenopausal and the control samples, While the result of premenopausal show that increased level of HMGB1 in comparison with the control sample. Highly significant decrease of VitaminD level of pre- and post-menopausal women in comparison with healthy women. While no significant result of AMH level and significant increase of HMGB1 level. A significant negative correlation of Total vitaminD level with HMGB1 level at both pre and post-menopausal women, on the other hand, insignificant correlation has been found between Vit. D and other parameters.

ملخص البحث :

Background: Menopause is a unique event in women's life it usually occurs naturally, most often after age 50 when woman has not menstruated in 12 consecutive months. This study was planned to assess the relationship between Vitamin D3 level, PAI-1 and HCG in Babylon women at age <50 years as pre-menopausal and> 50 years as post-menopausal. Methods: The sample were selected from a group of pre- and post-menopausal women, 30 and 50 respectively. All the tests were evaluated to measure Vitamin D3 level, PAI-1 and HCG level. The sample was collected between July 2019 and January 2020 at Merjan medical city GIT and Liver Center, Babylon province, Iraq. Results:The result of current study revealed that there are significant differences in vitamin D3 level in various age categories within postmenopausal women (p= 0.02) also there is no significant differences in PAI-1 and HCG with in these two groups, p= 0.08 and 0.07, respectively. Also, there is significant negative correlation between vitamin D3 and PAI-1 in postmenopausal women (p. value is 0.01). Conclusions: Indeed, postmenopausal women regarded as elderly, but they have sufficient vitamin D3 and normal PAI-I levels as markers for normal non fibrosis status.